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The formation of hypersensitivity occurs in the following ways: An immediate type reaction associated with the release of immunoglobulin E. It develops after 5-8 hours. Appears as local reactions or anaphylaxis. Delayed reaction. Systemic manifestation that occurs after 12-24 hours. Occurs in the form of urticaria, edema or anaphylactic reaction.

Tadalafil is a hormone.

A local manifestation may be due to improper administration of the drug - a thick needle is injected intradermally, the skin is injured during injection, an unsuccessful place is chosen, excessively chilled insulin is injected.

Hormones are chemicals that regulate the state of the cells of the body and are produced by special glands. The hormone insulin is the main regulator of glucose (sugar) levels in the blood. Insulin is produced in the pancreas. To be more specific, it is produced by beta cells in the islets of Langerhans of the pancreas. When we eat, glucose levels rise and insulin enters the bloodstream. Insulin acts as a key that unlocks the cell so it can take in the glucose molecule and use it as an energy source.

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Sugar is one of the best sources of energy for the body. The body gets it in various forms, but mostly from carbohydrates, which are broken down into glucose during digestion. Examples of high carb foods are pasta, rice, bread, potatoes, and of course all kinds of sweets.

The cells of a person with diabetes have problems utilizing glucose as a result of either a lack of cialis or resistance to it. Instead, the sugar is not delivered to the tissues, resulting in an increase in blood glucose levels.


People with type 1 diabetes must receive insulin injections every day. Every diabetic should know the exact dose of cialis calculated specifically for him or her. An overdose of insulin lowers the concentration of sugar in the blood.


If it gets too low, it can lead to coma or death. An overdose of insulin in a patient is treated with sugar in a form that contains as much of it as possible, such as a sugar cube or sweet juice. If the patient is in a coma, glucose must be injected directly into the bloodstream.

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If a diabetic gets too little insulin, he or she can go into a coma, just like an overdose of insulin. The two types of coma are very difficult to tell apart without checking the patient's blood glucose levels. If the levels are low, the patient is suffering from an insulin overdose. If the blood glucose level is high, the patient does not have enough insulin.

A nonspecific reaction to sugar is diagnosed in people who abuse sweets and drinks. The cause is hyperallergenic nutrition, heredity, dysbacteriosis, enzyme deficiency, metabolic and hormonal disorders. It can also be provoked by the deterioration of the functions of the digestive system due to bad habits. Allocate true and false allergies and intolerance to carbohydrates. They have similar symptoms: they may be accompanied by itching, rash, manifestations of dyspepsia, respiratory failure.

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True food allergy refers to the reaction of immune system cells to: glycoproteins (protein-carbohydrate compounds); polypeptides (some types of proteins and complex amino acids). Pseudo-allergy is the appearance of certain symptoms that develop without the participation of immune cells. More often it occurs against the background of diseases expressed by metabolic disorders, with a large intake of histamine from food, and for other reasons.

Carbohydrate intolerance refers to the inability of the gastrointestinal tract to break down and absorb them. Intolerance begins due to a lack of enzymes and is often manifested by pain, abdominal cramps, and diarrhea.

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Lipodystrophy is a thinning of the subcutaneous fat, which occurs in diabetics due to frequent injections of insulin in the same anatomical area. The fact is that in the injection zone, insulin can be absorbed with a delay and notcompletely penetrate into the desired tissues.
July 2, 2021

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This can lead to a change in the strength of its influence and thinning of the skin in this place. As a rule, modern drugs rarely have such a negative effect, but for prevention it is advisable to periodically change injection sites anyway. This will protect against lipodystrophy and keep the subcutaneous fat layer intact.
June 18, 2021

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By itself, lipodystrophy, of course, does not pose a threat to the patient's life, but it can become a serious problem for him. Firstly, due to lipodystrophy, the level of cholesterol in the blood rises, and because of this, there is a risk of developing cardiovascular diseases.
June 8, 2021
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Secondly, because of it, the physiological pH level of the blood can shift towards increasing acidity. A diabetic may begin to have problems with body weight due to a local disturbance of metabolic processes.

Immediate - occurs 15-30 minutes after insulin administration in the form of severe itching or changes in the skin: dermatitis, urticaria or redness at the injection site. Slow - it may take a day or more before symptoms appear.

Another unpleasant nuance in lipodystrophy is the occurrence of pulling pain in those places where the affected subcutaneous fat is located.

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